I-10 Eastbound is closed at mile marker 210 due to an accident and fish spill spill on the Bonnet Carre Spillway.
The crash, involving an 18-wheeler, happened around 3:30 a.m. near mile marker 214.
Viewers reported seeing fish scattered all across the roadway.
Drivers are being told to exit the interstate at US 51 and take Airline Hwy. as an alternate route.